臨牀消化器内科 Vol.15 No.1(4)


特集名 消化器疾患とQOL
題名 潰瘍性大腸炎とQOL
発刊年月 2000年 01月
著者 朝倉 均 新潟大学医学部第三内科
【 要旨 】 総体的QOLは,生物学的・生理学的変数が症候を規定し,さらにこれが機能的状態,をそして全般的な健康感を認識して導かれるものである.潰瘍性大腸炎におけるQOLを規定する病気からみた因子は,潰瘍性大腸炎の病型,病期(活動度),臨床的重症度,臨床経過,難治性,腸管内外合併症,腸切除などであるが,これらの病気全般の因子のみならず,SF36にみられるような身体的役割機能,社会的機能,身体的機能,一般的な精神的機能,情緒的役割機能,疼痛,バイタリティ,全般的健康感の8機能がQOLを左右する.疾患特異的尺度にはIBDQが用いられる.病気の治療によりQOL数値は改善するが,必ずしも病気の活動度はQOLを予見しない.しかし,IBDQ,病気の活動度,精神社会的機能指数を組み入れることにより,本症特有のQOLを出すことができる.
Theme Quality of Life in Gastroenterological Disorders
Title Quality of Life in Ulcerative Colitis
Author Hitoshi Asakura The Third Department of Internal Medicine, School of Medicine, Niigata University
[ Summary ] Overall quality of life is defined by general health perceptions, which are based on the functional and symptom status, defined by biological and physiological variables. Factors defining QOL in ulcerative colitis, from the viewpoint of disease states, are composed of not only general disease factors such as disease patterns, disease activity, clinical severity, clinical course, intractability, intestinal and extraintestinai complications, and post-intestinal resection states, but also eight functional items defined in SF36, such as physical role functioning, social functioning, physical functioniug, general mental functioning, cognitive functioning, pain, vitality, and general health perceptions. IBDQ is used to evaluate disease-specific QOL. Disease acitivity is not always a predictor of patient well being. Considering three factors jointly sucll as lBDQ measures, disease activity measures, and phychosocial functioning measures may be able to provide disease-specific QOL.
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