臨牀消化器内科 Vol.13 No.8(1)


特集名 安全な内視鏡的粘膜切除術
題名 食道のEMRC(食道癌)-- 透明プラスチックキャップを用いる方法(適応も含めて)
発刊年月 1998年 07月
著者 井上 晴洋 東京医科歯科大学医学部第一外科
【 要旨 】 食道表在癌のなかで,扁平上皮癌の深達度が粘膜固有層に留まる病変では,通常リンパ節転移を認めない.したがって,内視鏡的粘膜切除術などの局所療法の適応となる.われわれは透明キャップを用いる粘膜切除術を主として施行している初期の症例で穿孔と狭窄を1例ずつ経験しているが,いずれも現在は予防可能と考えている.他病死を含めた5年生存率は95%であり,適応を遵守すれば,きわめて安全かつ有用な方法で,術後のQOLの高い治療法である.
Theme Safety Procedures in Endoscopic Mucosectomy
Title Endoscopic Mucosal Resection for Esophageal Mucosal Cancer Utilizing the EMRC Technique
Author Haruhiro Inoue First Department of Surgery Tokyo Medical and Dental University
[ Summary ] Mucosal cancer displaying histological penetration is limited to the proper mucosal layer usually has no risk of lymph-node involvement. Therefore, it is an appropriate candidate for endoscopic mucosal resection. The authors developed an EMRC procedure using a transparent plastic cap. One handred fourty five cases received mucosal resection using this procedure and the other procedures. In our early treatments one perforation and one case of severe stenosis were encountered, and both patients were successfully treated. No recurrences were observed in clearly indicated cases. Use of EMR on m3 or sm1 patients is still controvercial because of about a 10% Iymph node involvement. In these cases the treatment of choice should be decided by the patients' physical conditions along with the patients' decisions aided by informed consent. Endoscopic mucosal resection is considered to be a safe and beneficial treatment for mucosal cancer of the esophagus, leading to complete recovery.
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