臨牀消化器内科 Vol.13 No.6(2-3)


特集名 消化器の前癌病変
題名 胃の前癌病変 (3) 胃切除後の残胃環境と臨床における問題点
発刊年月 1998年 06月
著者 大谷 吉秀 慶應義塾大学医学部外科
著者 北島 政樹 慶應義塾大学医学部外科 / 同 内視鏡センター
【 要旨 】 胃切除後の残胃粘膜には,胆汁や膵液の逆流による刺激や神経切除による脱神経支配など,手術が行われる前に比べて大きな環境変化が生じる.これらが残胃の発癌につながる可能性について述べるとともに,胃切除後のフォローアップの重要性や残胃発癌の予防として外科手術における工夫について概説する.
Theme Precancerous Lesions in the Digestive System
Title Mucosal Damage after Distal Gastrectomy-Importance of Prevention and Early Detection of Remnant Carcinoma
Author Yoshihide Otani Department of Surgery, School of Medicine, Keio University
Author Masaki Kitajima Department of Surgery, School of Medicine, Center for Diagnostic and Therapeutic Endoscopy, Keio University
[ Summary ] Jejunal reflux of bile and pancreatic juice into the remnant stomachis one of the major biological changes after distal gastrectomy, whichhas been considered to be associated with carcinoma in remnant stomach.Because of the poor prognosis, prophylaxis against the development ofremnant carcinoma seems important. The use of reflux-preventing operation is recommended. In order to find out in situ carcinoma, we recommendroutine endoscopic examinationof the patients begining 15 to 20 years after gastrectomy and obtaining multiple biopsy from the region of the stoma and from any mucosal abnormalities
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