| [ Summary ] |
A higher frequency of gastric cancer has been reported in the gastric remnant, especially after Billroth II-reconstruction. The gastric mucosa adjacent to the anastomosis is continuously exposed to bile reflux, and this results in foveolar hyperplasia and cystic proliferation of mucous glands in the remnant mucosa. Over the course of time, (pseudo-) pyloric glands become cystically dilated, showing so-called stomal gastritis. Characteristics of stomal cancers, which arise from this stomal gastritis, are somehow different from those of conventional types of cancers arising in the non-operated stomach ; most stomal cancers disclose gastric-type phenotypic expression, and their genetic abnormalities may be different from those of conventional types of gastric cancers. In this chapter, the character-istics and histogenesis of stomal gastritis and stomal cancers are discussed. |