| 特集名 | 潰瘍性大腸炎の治療の最先端 | |
|---|---|---|
| 題名 | 軽症例の診療と監視 | |
| 発刊年月 | 1997年 09月 | |
| 著者 | 岸 秀幸 | 東邦大学医学部第三内科 |
| 著者 | 藤沼 澄夫 | 東邦大学医学部第三内科 |
| 【 要旨 】 | 潰瘍性大腸炎はその臨床重症度より治療を選択する．軽症ではsalicylazosulfapyridine，mesalazineを中心に投与する．効果が期待できない場合に，直腸炎型ではbetamethasone坐剤を，左側結腸型ではprednisolone注腸療法を併用していく．また緩解導入後も監視を軽視することなく，患者とのよい関係を保ち，維持療法を継続し，定期的な検査を施行していくことが重要である． 軽症例でも再燃を繰り返す例では，臨床的重症度に偏重せず，内視鏡像，臨床経過を考慮し，一段階上の治療を選択していくのがよいと思われる． |
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| Theme | Advanced Therapy Ulcerative Colitis | |
|---|---|---|
| Title | Treatment and Follow-up of Mild Ulcerative Colitis | |
| Author | Hideyuki Kishi | Third Department of Internal Medicine |
| Author | Sumio Fujinuma | Third Department of Internal Medicine |
| [ Summary ] | Therapy for ulcerative colitis is selected on the basis of clinical severity. Mild cases are treated mainly with salicylazosulfapyridine and mesalazine. If there is no response, patients with proctitis-type disease are concomitantly given betamethasone suppositories and those with left-sided colonic involvement are given prednisolone enema therapy. Even after remission, patients should be carefully observed. A good patient-physician relationship, continuation of maintenance therapy, and periodic follow-up examinations are essential to successful long-term management of this disease. Regardless of clinical severity, patients with mild ulcerative colitis who have repeated flare-ups should receive the next therapeutic step, if indicated by endoscopic findings and clinical course. |
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