Theme |
How Can We Realize the Philosophy of Chronic Kidney Disease-Mineral and Bone Disorder? |
Title |
Dialysis related amyloidosis and CKD-MBD |
Author |
Junichiro James Kazama |
Department of Advanced Disaster Medical and Emergency Critical Care Center, Niigata University Medical and Dental Hospital |
Author |
Toru Hirano |
Department of Orthopedic Surgery, Niigata University Medical and Dental Hospital |
Author |
Suguru Yamamoto |
Department of Nephrology and Rheumatology, Niigata University Medical and Dental Hospital |
[ Summary ] |
Osteolytic lesions caused by inflammatory boneresorption around Aβ2M amyloid deposition are referred to as dialysis related amyloidosis osteopathy (DRAO). Dialysis related amyloidosis syndromes, including DRAO are currently not considered to be related to CKD-MBD. Since this disease is involved with multiple local lesions, it is sometimes the object of surgical treatments. Therefore, physicians must carefully look for symptoms of this condition in the daily clinical practices. |