| 特集名 | 維持透析患者の消化管疾患 | |
|---|---|---|
| 題名 | 維持透析患者の味覚障害 | |
| 発刊年月 | 2006年 07月 | |
| 著者 | 戸田 孝之 | 土浦協同病院内科 |
| 著者 | 佐藤 文絵 | 土浦協同病院内科 |
| 著者 | 藤井 徹郎 | 土浦協同病院内科 |
| 著者 | 松井 則明 | 土浦協同病院内科 |
| 【 要旨 】 | 味覚障害のうち亜鉛欠乏性と特発性は，亜鉛補充療法が有効と報告されている．血清亜鉛濃度は血液透析患者では健常人に比べて低下しているが，亜鉛の血清への分布量は少なく体内の亜鉛欠乏を必ずしも反映しないため，簡便で有用な指標の発見が待たれる．維持血液透析患者では味覚障害が高頻度にみられ，自覚症状は乏しいと報告されている．自験例でも味覚障害は高頻度に存在し，濾紙ディスク法の鼓索神経領域の認知閾値測定において17人中5人で3味質以上最高濃度でも認知できなかった．塩味の認知閾値を全口腔法で検査したところ，10人中4人で塩化ナトリウム濃度0.625 %以上であった．高度な味覚減退の訴えは1人のみで認められた． | |
| Theme | Diseases of Alimentary Tract in Maintenance Dialysis Patients | |
|---|---|---|
| Title | Taste disorder experienced by maintenance dialysis patients | |
| Author | Takayuki Toda | Department of Nephrology, Tsuchiura Kyodo General Hospital |
| Author | Fumie Satou | Department of Nephrology, Tsuchiura Kyodo General Hospital |
| Author | Tetsurou Fujii | Department of Nephrology, Tsuchiura Kyodo General Hospital |
| Author | Noriaki Matsui | Department of Nephrology, Tsuchiura Kyodo General Hospital |
| [ Summary ] | It has been reported that zinc substitution therapy is effective for zinc deficiency related taste disorders and idiopathic taste disorders. When compared to healthy persons, serum zinc levels of hemodialysis patients are lower. Because there is a low level of zinc distribution in the serum, degradation of serum zinc values does not always lead to internal zinc deficiency. Medical treatment of taste disorders will progress through the development of a more useful zinc deficiency index. It has been reported that taste disorders are often present in maintenance hemodialysis patients, and subjective symptoms are usually mild. Taste disorders were often present in the cases we examined. We measured the cognition threshold of the chorda tympani area using a filter paper disc test. The cognition threshold measured the qualities of taste which were more common in three to five out of seventeen maintenance dialysis patients. The cognition threshold for sodium chloride which we examined by all oral cavity methods was higher than 0.625 % in four out of ten dialysis patients. The subjective advanced hypogeusia symptoms were found in only one case. |
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