Theme |
Current Topics in Monitoring Technologies for Dialysis Therapy |
Title |
Shift in tissue oxygen pressure possibly preceding abrupt blood pressure drop |
Author |
Tetsuzo Agishi |
Blood Purification Center, Itabashi Chuo Medical Center |
Author |
Makoto Sakauchi |
Blood Purification Center, Itabashi Chuo Medical Center |
Author |
Toshihisa Hoshino |
Blood Purification Center, Itabashi Chuo Medical Center |
Author |
Makoto Akamatsu |
Blood Purification Center, Itabashi Chuo Medical Center |
Author |
Toshio Sato |
Department of Clinical Engineering, Toin University of Yokohama |
Author |
Norimichi Kawashima |
Department of Clinical Engineering, Toin University of Yokohama |
[ Summary ] |
Instability in the circulatory system is presently a prominent and serious symptom in maintenance hemodialysis patients, due to increased patient age and prolongation of dialysis period. An abrupt blood pressure drop frequently occurs during hemodialysis in these patients and sometimes may even threaten their lives. Therefore, anticipation of a blood pressure drop, if possible even a few minutes before initiation of the event, may insure their safety. A system, which continuously and instantaneously monitors systolic blood pressure (BP), tcPO2, tcPCO2 and tissue blood flow, was constructed. The data on BP and tcPO2 was not direct or disorganized, but analyzed by applying a one minute derivative method and a moving average method, using personal computer transformation, suggesting that tcPO2 may have shifted approximately 360 seconds before a BP drop developed. More data on BP and tcPO2 should be accumulated and analyzed for installation of such monitoring systems into practical hemodialysis control consoles. |