| [ Summary ] |
Although patients acquire good renal function (s-Cr<2mg/dl) after kidney transplantation, in some recipients the level of 1,25(OH)2 D3 is not always within normal ranges. Secondary hyperparathyroidism sometimes persist after renal transplantation. Even when PTH level is high, the level of 1,25(OH)2D3 is below the normal range in these patients. The relative shortage 1,25(OH)2D3 in these recipients contributes to persistent secondary hyperpara thyroidism, renal phosphate wasting and bone disease, after kidney transplant. The supplementation of active vitamin D in normocal cemic renal transplant recipients with good renal function, high PTH level and low level of 1,25(OH)2D3 will help to improve persistent secondary hyperparathyroidism, hypophos phatemia and bone loss after kidney transplantation. However, careful follow-up for hyper calcemia and deterioration of graft functioning are required. |