| Theme |
Recent advance in diagnosis and management of colorectal tumors associated with inflammatory bowel disease |
| Title |
An investigation to optimize surveillance colonoscopy to detect ulcerative colitis-associated neoplasia : A comparison between panchromoendoscopy and pancolonic narrow band imaging observation |
| Author |
Kenji Watanabe |
Division of Internal Medicine, Department of Inflammatory Bowel Disease, Hyogo College of Medicine / Department of Intestinal Inflammation Research, Hyogo College of Medicine |
| Author |
Nobuyuki Hida |
Department of Intestinal Inflammation Research, Hyogo College of Medicine |
| Author |
Takako Miyazaki |
Department of Intestinal Inflammation Research, Hyogo College of Medicine |
| Author |
Toshiyuki Sato |
Department of Intestinal Inflammation Research, Hyogo College of Medicine |
| Author |
Mikio Kawai |
Division of Internal Medicine, Department of Inflammatory Bowel Disease, Hyogo College of Medicine / Department of Intestinal Inflammation Research, Hyogo College of Medicine |
| Author |
Koji Kamikozuru |
Department of Intestinal Inflammation Research, Hyogo College of Medicine |
| Author |
Tetsuya Takagawa |
Division of Internal Medicine, Department of Inflammatory Bowel Disease, Hyogo College of Medicine / Department of Intestinal Inflammation Research, Hyogo College of Medicine |
| Author |
Yoko Yokoyama |
Department of Intestinal Inflammation Research, Hyogo College of Medicine |
| Author |
Shiro Nakamura |
Department of Intestinal Inflammation Research, Hyogo College of Medicine |
| [ Summary ] |
We performed a prospective multicenter randomized controlled trial to compare between panchromoendoscopy and pancolonic narrow band imaging (NBI) observation as tools for surveillance colonoscopy in patients presenting with ulcerative colitis. This Navigator Study revealed that pancolonic NBI observation was not inferior to panchromoendoscopy for the detection of neoplastic lesions. The quality of a surveillance colonoscopy can be improved by the detection of suspected lesions and following characterization, it can help in demarcating a lesion and its depth and establishing the differential diagnoses for ulcerative colitis-associated vs. sporadic neoplasia. The detection rate of pancolonic NBI observation used for surveillance colonoscopy is not inferior to that observed with panchromoendoscopy or that observed in previous reports. |