| [ Summary ] |
Behçet's disease (BD) is a systemic inflammatory disease of unknown origin whose four main symptoms are ① recurrent oral ulcers, ② ocular symptoms, ③ epidermal symptoms and ④ genital ulcers. To diagnose intestinal BD, it is necessary to determine the diagnostic criteria have been met. If the diagnostic criteria for BD do not exist, even if there are lesions typically associated with intestinal BD, a diagnosis of intestinal BD or simple ulcers (SU) may be made. The pathology of intestinal BD and SU have not been elucidated, therefore, it is difficult to distinguish between the two diseases by employing histopathological findings. Treatment of intestinal BD is updated every time a consensus statement is revised. Anti-TNF α antibody treatment (ADA, IFX) was standardized in the 2013 revised edition. Intestinal BD is thought to be a poor prognostic factor, because of the risk of perforation and bleeding and high recurrence rates after surgery. Therefore, the establishment of a therapeutic strategy is an urgent task. Development of new clinical guidelines for daily practice is in progress. |