INTESTINE Vol.21 No.5(5)


連載名 第26回 大腸IIc研究会 Young award
題名 短期間で形態および拡大観察所見が変化したSSA/P由来のT1癌の1例
発刊年月 2017年 09月
著者 山下 賢 広島大学病院内視鏡診療科
著者 岡 志郎 広島大学病院消化器・代謝内科
著者 田中 信治 広島大学病院内視鏡診療科
著者 有廣 光司 広島大学病院病理診断科
著者 嶋本 文雄 広島修道大学健康科学部
著者 茶山 一彰 広島大学病院消化器・代謝内科
【 要旨 】 症例は68歳男性,盲腸に径10mm大の0-Is型病変を認めた.通常観察およびNarrow Band Imaging (NBI)拡大・色素拡大内視鏡観察から,sessile serrated adenoma/polyp (SSA/P)由来のcTis~T1a癌と診断し,内視鏡的摘除の方針とした.しかし,初回検査から12日後の治療時には,病変の丈はやや低くなり,表面が発赤調を呈していた.NBIおよび色素拡大内視鏡観察では,初回精査時と比較して不整さが増していた.cT1bの可能性も考慮したが,摘除生検目的に内視鏡的一括摘除を施行した.病理組織学的所見は,tub1 with SSA/P, pT1b (1,500 µm), budding grade 1, ly0 (D2-40), v0 (VB), pHM0, pVM0であった.
Series
Title Case of T1 carcinoma resulting from SSA/P after changed morphology observed in short term magnified observation
Author Ken Yamashita Department of Endoscopy, Hiroshima University Hospital
Author Shiro Oka Department of Gastroenterology and Metabolism, Hiroshima University Hospital
Author Shinji Tanaka Department of Endoscopy, Hiroshima University Hospital
Author Koji Arihiro Department of Anatomical Pathology, Hiroshima University Hospital
Author Fumio Shimamoto Faculty of Health Sciences, Hiroshima Shudo University
Author Kazuaki Chayama Department of Gastroenterology and Metabolism, Hiroshima University Hospital
[ Summary ] A 68-year old man was admitted for treatment of a colon tumor in the caecum 10 mm in diameter. Standard colonoscopy, magnifying endoscopy with narrow band imaging (NBI) and magnifying chromoendoscopy suggested cTis ˜ T1a carcinoma arising from sessile serrated adenoma/polyp (SSA/P). We performed endoscopic mucosal resection of this tumor. However, at the time of treatment 12 days after the initial examination, the height of the lesion had decreased somewhat, the surface was reddish. With NBI magnification and pit pattern findings. The surface pattern of the tumor had obviously become more irregular compared with the initial examination. We performed precutting endoscopic mucosal resection before total excisional biopsy of this tumor. Histopathological findings were carcinoma (tub1) with SSA/P, pT1b (SM 1,500 µm), budding grade 1, ly 0 (D2-409, v0 (VB), pHM0, pVM0. We report a case of pT1b carcinoma arising from SSA/P which changed morphology and magnifing findings in a short period.
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