| Theme |
Impacts of intestinal microbiota |
| Title |
Functional gastrointestinal disorders and gut microbiota : Psychological stress and gut microbiota |
| Author |
Takeshi Takajo |
Department of Internal Medicine, National Defense Medical College |
| Author |
Ryota Hokari |
Department of Internal Medicine, National Defense Medical College |
| [ Summary ] |
Stress has become the cause of a variety of physical and psychological disorders in modern society. In Japan, the concept of stress related conditions has begun to be recognized. However the relationship between the digestive system and the central nervous system has been recognized since ancient times. On the other hand, gut microbiota are being watched with keen interest as one of the pathogenic mechanisms of stress related psychiatric disorders. In fact, we can find previous reports concerning evidence of that relationship, termed the "microbiotagut-brain axis". We referred previous reports and reviewed concepts involving stress, the relationship between the pathophysiology of stress and gut microbiota, as well as the relationship between stress related psychiatric disorders and gut microbiota. |