| Theme |
Impacts of intestinal microbiota |
| Title |
Methods for comprehensive analysis of human gut microbiomes |
| Author |
Wataru Suda |
Department of Microbiology and Immunology, Keio University School of Medicine / Laboratory for Microbiome Sciences, RIKEN Center for Integrative Medical Sciences (IMS) |
| Author |
Masahira Hattori |
Graduate School of Advanced Science and Engineering, Waseda University / Laboratory for Microbiome Sciences, RIKEN Center for Integrative Medical Sciences (IMS) |
| [ Summary ] |
Analysis of the human gut microbiome, collective genomes of over 100 trillion intestinal microbial cells which form a complex bacterial community, has recently become more practical due to remarkable advances in sequencing technologies. Metagenomic approaches using next-generation sequencing (NGS) have enabled us to comprehensively analyze genes/functions and species composition in the human gut microbiome, strongly suggesting that the human gut microbiome has profound influences on various host physiologies including disease. We describe the analytical process of metagenomic data generated from NGS for characterization of the ecological and functional features of human gut microbiomes. |