Theme |
Novel therapeutic strategy for ulcerative colitis |
Title |
Surgical treatment of ulcerative colitis |
Author |
Hiroki Ikeuchi |
Inflammatory Bowel Disease Center, Hyogo College of Medicine / Department of Surgery, Hyogo College of Medicine |
Author |
Motoi Uchino |
Inflammatory Bowel Disease Center, Hyogo College of Medicine / Department of Surgery, Hyogo College of Medicine |
Author |
Hiroki Matsuoka |
Inflammatory Bowel Disease Center, Hyogo College of Medicine / Department of Surgery, Hyogo College of Medicine |
Author |
Toshihiro Bando |
Inflammatory Bowel Disease Center, Hyogo College of Medicine / Department of Surgery, Hyogo College of Medicine |
Author |
Akihiro Hirata |
Inflammatory Bowel Disease Center, Hyogo College of Medicine / Department of Surgery, Hyogo College of Medicine |
Author |
Naohiro Tomita |
Department of Surgery, Hyogo College of Medicine |
[ Summary ] |
Surgical treatment is indicated for patients with intractable ulcerative colitis. Approximately 70 % of these UC cases are considered to be intractable. Cancer related dysplasia is the next most common. The need for surveillance of these patients is expected to increase in near future due to a projected increase in the overall number of cancer cases as well as projected extension of treatmet periods. The perioperative prognoses for elderly UC patients who undergo emergency surgery are especially poor. Postoperative success rates for patients with functioning pouches is considered to be acceptable at approximately 92 % twenty years after surgery. On the other hand, that rate is considered to be unsuitable for patients with intractable pouchitis and patients whose diagnosis has later been changed to one of Crohn's disease. |