Theme |
Invasive colorectal cancer current status and practical issues of depth 1,000μm |
Title |
Clinical issues for diagnostic strategies to measure depth of SM invasion 1,000μm, post EMR |
Author |
Shoichi Saito |
Dept. of Endoscopy, The Jikei University. School of Medicine |
Author |
Toshiki Nikami |
Dept. of Internal Medicine, The Jikei University. School of Medicine, |
Author |
Naoto Tamai |
Dept. of Endoscopy, The Jikei University. School of Medicine |
Author |
Tomohiko Ohya |
Dept. of Endoscopy, The Jikei University. School of Medicine |
Author |
Hiroyuki Aihara |
Dept. of Endoscopy, The Jikei University. School of Medicine |
Author |
Takeshi Suzuki |
Dept. of Endoscopy, The Jikei University. School of Medicine |
Author |
Tomohiro Kato |
Dept. of Endoscopy, The Jikei University. School of Medicine |
Author |
Hisao Tajiri |
Dept. of Endoscopy / Dept. of Internal Medicine, The Jikei University. School of Medicine |
Author |
Masahiro Ikegami |
Dept. of Pathology, The Jikei University. School of Medicine |
[ Summary ] |
We studied submucosal invasive cancers (SM-Ca.), as to whether it is possible to expand the indications for endoscopic treatment or not. During the period between 2003 and 2011, one hundred sixty SM-Ca. cases, excised endoscopically or surgically in our hospital were studied. The rate of lymph node (LN) metastasis was 10.6 % (17/160). Only 8.8 % (3/34) of the cases, performed required additional surgical resection after endoscopic treatment and revealed LN metastasis. The mean depth of invasion (4,127.5±1,183.5 μm) in SM-Ca. with LN metastasis was deeper compared to cases without LN metastasis. The minimum depth was 2,250μm in cases with LN metastasis. Of 41 cases (SM-S; 22, SM-M; 19) were followed-up without additional surgical resection and were observed closely (mean duration:36.9 month). In order to decrease the number of cases requirins further surgery after endoscopic treatment, the curable criterion for complete resection may need to include lesions ranging from 1,000μm in SM-Ca. |