INTESTINE Vol.10 No.3(5)


特集名 拡大内視鏡による質的診断の進歩 -- VI型pitから血管構造・Endo-Cystoscopy・IBDまで
題名 Endo-Cytoscopyは異型度診断に迫れるか
発刊年月 2006年 05月
著者 佐々木 広仁 昭和大学横浜市北部病院消化器センター
著者 笹島 圭太 昭和大学横浜市北部病院消化器センター
著者 樫田 博史 昭和大学横浜市北部病院消化器センター
著者 井上 晴洋 昭和大学横浜市北部病院消化器センター
著者 田中 淳一 昭和大学横浜市北部病院消化器センター
著者 大塚 和朗 昭和大学横浜市北部病院消化器センター
著者 工藤 進英 昭和大学横浜市北部病院消化器センター
著者 浜谷 茂治 昭和大学横浜市北部病院病理部
著者 塩川 章 昭和大学横浜市北部病院病理部
【 要旨 】 要旨はありません。
Theme Development of diagnosis of magnifying endoscopy
Title The prediction of the depth of invasion by checking cellular atypia with Endo-Cytoscopy systems
Author Hirohito Sasaki Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Keita Sasajima Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Hiroshi Kashida Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Haruhiro Inoue Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Junichi Tanaka Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Kazuo Ohtsuka Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Shin-ei Kudo Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Shigeharu Hamatani Department of Pathology, Showa University Northern Yokohama Hospital
Author Akira Shiokawa Department of Pathology, Showa University Northern Yokohama Hospital
[ Summary ] It can be said that magnifying colonoscopy has nearly been established as the primary tool in the diagnosis of early cololectal cancer. Magnified observation of intra papillary capillary loops (IPCL) in the esophagus is also considered.
Histological findings of gastrointestinal lesions are made on the basis of light-microscopic examination of hematoxylin-eosin stained thin-slice specimens. Endo-Cytoscopy (E-C) systems, a type of novel "ultra-high" magnifying endoscopy, enable cellular level microscopic observation in vivo and can be applied clinically. They provide realtime histological images, in vivo, that correspond well with those of hematoxylin-eosin stained microscopic images. A study to clarity the usefulness of E-C in the diagnosis of colorectal neoplasms was conducted. Diagnostic accuracy was over 90 % in E-C compared with the final pathological diagnosis.
We expect more accurate prediction of the depth of invasion by checking cellular atypia with E-C systems.
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