臨牀透析 Vol.25 No.13(2-2)


特集名 CKD患者の輸液と経腸栄養の指針 -- ステージ4・5患者への対策
題名 [各論]II. 糖質輸液の指針
発刊年月 2009年 12月
著者 長澤 康行 大阪大学大学院医学系研究科老年腎臓内科
【 要旨 】 慢性腎不全において栄養管理が必要なことは健常人と同様である.さらに腎不全では低たんぱく高エネルギーが原則となり,かつ輸液療法が必要な状況ではアミノ酸利用が低下するため,より糖質輸液が重要となる.慢性腎不全の場合,輸液を行うスペースが十分にないことがある.そのようなとき,血液浄化療法を行うことで除水を行い,そのうえで十分な栄養を投与する必要がある.糖質輸液を開始するときは,目標投与量までに段階的にステップアップを行う.血糖管理は重要であり,輸液速度・糖濃度などのメニューを変更後2 時間程度で必ず評価を行う必要があり,その後も毎日評価を行う.血液透析患者においては,透析時に栄養輸液を行うIDPN(intra-dialysis parenteral nutrition)という方法もある.
Theme Strategies of Parenteral and Enteral Nutrition in Patients with Chronic Kidney Disease Especially at Stages 4 and 5
Title Glyconutrition of patient with the chronic kidney disease stages 4, 5 and 5D
Author Yasuyuki Nagasawa Department of Geriatric Medicine & Nephrology, Osaka University Graduate School of Medicine
[ Summary ] It is important that patients with end stage renal disease (ESRD), as well as those without ESRD, control their nutrition status. Low protein, high calorie diets are favorable for ESRD patients. Moreover, in cases where intravenous hyperalimentation (IVH) is necessary, it may be difficult to metabolize amino acids. Therefore, an adequate supply of glucose becomes more important. If there is no space for IVH, it is necessary to reduce fluid volume with hemodialysis in order to supply adequate nutrition. Glucose infusions should begin with low grade glucose concentrations and increase incrementally to adequate levels. The control of blood glucose levels is important, and those levels must be evaluated every two hours after changeing IVH routines such as the rate of infusion, or glucose concentrations. Glucose levels should be evaluated every day even though there has been no change in IVH routines. IDPN (intra-dialysis parenteral nutrition) is an alternative way to supply nutrition for hemodialysis patients.
戻る