INTESTINE Vol.25 No.4(1)


特集名 大腸Ⅱc─革命のその後
題名 大腸Ⅱcの臨床のあゆみと現状
発刊年月 2021年 12月
著者 工藤 進英 昭和大学横浜市北部病院消化器センター
著者 一政 克朗 昭和大学横浜市北部病院消化器センター
著者 望月 健一 昭和大学横浜市北部病院消化器センター
【 要旨 】 X線診断と内視鏡診断による早期癌診断のスパイラルアップのなかで“幻の癌”とされた大腸Ⅱc病変が発見されたのが1977年のことである.その後,筆者らは数多くの大腸Ⅱc病変を発見し,陥凹型腫瘍こそが大腸癌発育のメインルートと唱え,これにde novo癌としての位置付けを与えた.『早期大腸癌』の発刊や「大腸Ⅱc研究会」の立ち上げにより,大腸Ⅱc病変の実態と本質に迫りⅡcの重要性の啓蒙に努めてきた.ここでは筆者らが中心となり取り組んできた人工知能や遺伝子解析といった最新の知見も交えて,大腸Ⅱcのこれまでの歴史を振り返る.
Theme Depressed type colorectal cancer -- Revolution and since then
Title History and current status of 0-IIc colorectal lesions
Author Shin-ei Kudo Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Katsuro Ichimasa Digestive Disease Center, Showa University Northern Yokohama Hospital
Author Kenichi Mochizuki Digestive Disease Center, Showa University Northern Yokohama Hospital
[ Summary ] In 1977, a colorectal 0-IIc lesion, which was previously regarded as a "phantom cancer," was detected during the increased occurrences of early cancer diagnosis by radiography and endoscopy. Subsequently, the authors detected many colorectal 0-IIc lesions. They suggested that development of depressed lesions was the main route towards colorectal cancer development, and considered the lesions as de novo cancer. By publishing "Early Colorectal Cancer" and launching "Annual Meeting on Depressed Colorectal Cancer," we have been trying to spread the importance of 0-IIc colorectal lesions. Here, we look back on the history of 0-IIc, including the latest developments, such as artifi cial intelligence and gene analysis, which the authors are mainly working on.
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