Theme |
Clinical characteristics of fecal immunochemical test (FIT) negative colorectal cancer |
Title |
FIT-positive colorectal cancers versus FIT negative colorectal cancers: From the viewpoint of population-based screening |
Author |
Kinichi Hotta |
Division of Endoscopy, Shizuoka Cancer Center |
Author |
Takahisa Matsuda |
Cancer Screening Center, National Cancer Center Hospital / Endoscopy Division, National Cancer Center Hospital / Division of Screening Technology, Center for Public Health Sciences, National Cancer Center |
Author |
Hiroaki Ikematsu |
Department of Endoscopy, National Cancer Center Hospital East |
Author |
Yasuo Kakugawa |
Cancer Screening Center, National Cancer Center Hospital / Endoscopy Division, National Cancer Center Hospital |
Author |
Kenichiro Imai |
Division of Endoscopy, Shizuoka Cancer Center |
Author |
Sayo Ito |
Division of Endoscopy, Shizuoka Cancer Center |
Author |
Toshio Uraoka |
Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine |
Author |
Yoshikatsu Koga |
Exploratory Oncology Research & Clinical Trial Center, National Cancer Center |
Author |
Yutaka Saito |
Endoscopy Division, National Cancer Center Hospital |
[ Summary ] |
The characteristics of fecal immunochemical test (FIT)-negative colorectal cancers (CRCs) were investigated based on the results of a populationbased screening trial using two-sample-FIT and total colonoscopy performed in Oshima, Tokyo. All FIT negative CRCs were intramucosal cancers and were completely treated by endoscopic resections. FIT-negative CRCs had the trend of early stage, right-sided, and flat type compared to the FIT positive CRCs. Development of new, effective, and organized screening methods combined FIT and colonoscopy are desired. |