Theme |
Ulcerative lesions in the ileocecal region |
Title |
NSAID-induced ileo-cecal and colonic mucosal injury |
Author |
Takuya Inoue |
Second Department of Internal Medicine, Osaka Medical College |
Author |
Mitsuyuki Murano |
Murano Clinic |
Author |
Ken Narabayashi |
Second Department of Internal Medicine, Osaka Medical College |
Author |
Sadaharu Nouda |
Second Department of Internal Medicine, Osaka Medical College |
Author |
Takanori Kuramoto |
Second Department of Internal Medicine, Osaka Medical College |
Author |
Kumi Ishida |
Second Department of Internal Medicine, Osaka Medical College |
Author |
Yosuke Abe |
Second Department of Internal Medicine, Osaka Medical College |
Author |
Eiji Umegaki |
Second Department of Internal Medicine, Osaka Medical College |
Author |
Kazuhide Higuchi |
Second Department of Internal Medicine, Osaka Medical College |
[ Summary ] |
Non-steroidal anti-inflammatory drugs (NSAIDs) such as low-dose aspirin are widely used and reduce the risk of vascular events in patients with cardio- and cerebrovascular diseases. On the other hand, NSAIDs are well known to cause adverse effects such as gastroduodenal mucosal lesions. Ileocecal and colonic mucosal lesions can also be caused by NSIAD treatment. More recently, NSAIDs have been reported to also induce microscopic colitis, in forms such as collagenous colitis especially in elderly women. |