Theme |
Small colorectal cancer with high malignant potential |
Title |
Endoscopic findings concerning malignancy potential of small invasive colorectal cancer |
Author |
Akiko Chino |
Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research |
Author |
Yuko Hayashi |
Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research |
Author |
Masahiro Igarashi |
Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research |
Author |
Mizuka Imai |
Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research |
Author |
Teruhito Kishihara |
Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research |
Author |
Naoyuki Uragami |
Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research |
Author |
Yoshiro Tamegai |
Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research |
Author |
Yoshiya Fujimoto |
Digestive Surgery, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research |
Author |
Masashi Ueno |
Digestive Surgery, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research |
[ Summary ] |
Our study investigated 39 cases of submucosal invasive colorectal cancer 10 mm or less in size from 2005 to 2011. The endoscopic findings for malignancy potential were coexistent depressions with either protruding or sessile features or only depressed lesions. For that reason small lesions consisting of depressed lesions were considered to be nonpolypoid growths (NPG). Most were adenocarcinoma without being considered to be adenomas pathologically. This suggested they were de novo cancer. Those cases were very likely to develop deep invasion of the submucosa. Lymph node metastatic rates were also high. However, small polyps were difficult to observe in terms of features. Indigo-carmine dye spraying, with magnified NBI and magnified observation is useful in these cases. |