INTESTINE Vol.12 No.5(1-2-1)


特集名 10 mm以下の大腸SM以深癌
題名 小型大腸癌の臨床病理学的特徴 -- 内視鏡治療の是非 (2) 大きさ別の検討から a. 径10 mm以下の大腸SM癌の取り扱い
発刊年月 2008年 09月
著者 毛利 律生 広島大学病院光学医療診療部
著者 岡 志郎 広島大学病院光学医療診療部
著者 田中 信治 広島大学病院光学医療診療部
著者 金尾 浩幸 広島大学病院消化器内科
著者 平田 真由子 広島大学病院消化器内科
著者 吉田 成人 広島大学病院光学医療診療部
著者 茶山 一彰 広島大学病院消化器内科
【 要旨 】 要旨はありません。
Theme Small invasive cancer of colon and rectum less than 10 mm
Title Clinicopathological characteristics and treatment of cancer with SM invasion in a colorectal tnmor measuring 10 mm or less in size
Author Ritsuo Mouri Department of Endoscopy, Hiroshima University Hospital
Author Shiro Oka Department of Endoscopy, Hiroshima University Hospital
Author Shinji Tanaka Department of Endoscopy, Hiroshima University Hospital
Author Hiroyuki Kanao Department of Gastroenterology, Hiroshima University Hospital
Author Mayuko Hirata Department of Gastroenterology, Hiroshima University Hospital
Author Shigeto Yoshida Department of Endoscopy, Hiroshima University Hospital
Author Kazuaki Chayama Department of Gastroenterology, Hiroshima University Hospital
[ Summary ] The clinicopathological characteristics of small colorectal tumors measuring 10 mm or less in size were studied. Treatment of colorectal cancer with SM invasion was specifically considered. Lesions with depressions tend to be highly malignant even if they are small. Therefore, it is important to perform endoscopic observations while carefully searching for the presence of depressions in small colorectal tumors. If there is any possibility of such depressions, then either additional chromoendoscopy or magnifying endoscopy is required.
The rate of lymph node metastasis in small colorectal cancers (10 mm or less in size) with SM invasion was investigated during surgical resections. There was no metastasis in lesions 5 mm or less in size. In lesions measuring 6 mm to 10 mm in size, the rate of lymph node metastasis was 5.3 % overall, while it was 11 % in lesions with depressions.
In lesions measuring 5 mm or less in size, endoscopic treatment with total biopsies should be carried out for lesions with any possibility of SM invasion. Furthermore, treatment should be determined based on the histopathological findings. Lesions measuring from 6 mm to 10 mm should be treated in the same way as lesions larger than 10 mm.
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