| 特集名 | IIc由来のsm癌の転移 | |
|---|---|---|
| 題名 | 各々の定義によるIIcおよびIIc由来sm癌の転移と転移危険因子 (3) 粘膜内残存腫瘍病変からみた大腸sm癌の由来推定肉眼型と転移 | |
| 発刊年月 | 2006年 03月 | |
| 著者 | 大倉 康男 | 杏林大学医学部病理学 |
| 著者 | 知念 克哉 | 杏林大学医学部病理学 |
| 著者 | 松本 祐文 | 杏林大学医学部病理学 |
| 【 要旨 】 | 要旨はありません。 | |
| Theme | Metastasis in colorectal submucosal cancer of IIc origin | |
|---|---|---|
| Title | Study on colorectal carcinoma metastasis with submucosal invasion, estimating original form from remnant mucosal neoplasia | |
| Author | Yasuo Ohkura | Department of Pafhology, Kyorin Universify School of Medicine |
| Author | Katsuya Chinen | Department of Pafhology, Kyorin Universify School of Medicine |
| Author | Hirohumi Matsumoto | Department of Pafhology, Kyorin Universify School of Medicine |
| [ Summary ] | Fifty three cases of colorectal carcinoma with submucosal invasion were examined in relation to the original forms of remnant mucosal neoplasia and were divided into five groups ; the Fc type (originating from superficial depressed lesions), the Fac type (originating from superficial elevated lesions with depressions), the Fa type (originating from superficial elevated lesions), the Fu type (originating from superficial lesions but of unknown origin) and the P type (originating from polypoid lesions). Thirty seven cases (70 %) were of the F type. Most colorectal carcinomas with submucosal invasion had developed from the superficial type. Measurements of the mucosal neoplasia, remnant area in the most of the Fc type and the Fu type showed easily collapsing mucosal areas, which were different from the Fac type, the Fa type and the P type. Mean size of the Fc type was smaller than the other four types. Most of the Fc type invaded deeper layers of the suhmucosa, and resembled the Fu type. From these results, it was supposed that most Fu type tumors had onginated from the Fc type. There were six cases of carcinomas with metastasis, which were massively invasive. The two Fc type cases, the Fa type and the Fu type showed lymph nodal metastases. By examining many histological parameters, there was no feature observed to closely relate to metastasis. It was difficult to reveal the origins of invasive carcinoma, some of which were collapsed with a small or no mucosal lesions. From the data obtained, superficial colorectal carcinomas are the main lesions developing in to advanced ones. The superficial depressed type has a great tendency of lymph node metastasis. |
|