Theme |
Diet as Etiologic Factors and Therapeutic Tools in Digestive Diseases |
Title |
Genomics and Proteomics for Food Factor Science in Digestive Tract |
Author |
Yuji Naito |
Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine |
Author |
Hisashi Arikuni |
Yokohama Lab., Biomarker Science Co. Ltd. |
Author |
Hitoshi Kojyo |
Yokohama Lab., Biomarker Science Co. Ltd. |
Author |
Toshikazu Yoshikawa |
lnflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine |
[ Summary ] |
By using a molecule such as that found in a gene, a protein, an enzyme or a metabolite as biomarker, any study that examines ?scientifically functionality of food in digestive tract disease will be successful in producing positive economic results. To prevent digestive tract diseases, it is necessary to develop a method to diagnose the pre-disease stage or high risk groups associated with these disease. For a search method, we used genomic, proteomic, or metabolomic approaches, employing GeneChips, SELDI-TOF-MS, and LC-MS. In this report, we discussed the present situation and the future of functional food science in relation to digestive tract diseases. |