Kidney and Metabolic Bone Diseases Vol.23 No.1(7)

Theme Lifestyle-related diseases and fracture risk
Title Osteoporosis and medical treatment for lifestyle related diseases
Publish Date 2010/01
Author Ryo Okazaki Third Department of Medicine, Teikyo University Chiba Medical Centere
[ Summary ] Some drugs that are used to treat lifestyle related diseases have effects on bone. Thiazolidinediones, which are anti-diabetic agents, have been shown to be associated with increased risk of fractures. Statins, which lower serum cholesterol levels, were expected to be beneficial for bone based on their potent effects on bones seen in experiments. However, clinical studies have revealed that statins have little, if any, effect on bone.
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