| Theme |
Development of diagnosis of magnifying endoscopy |
| Title |
Magnified observation of microvascular architecture of colorectal lesions employing a Narrow Band Imaging system |
| Author |
Yasushi Sano |
Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East |
| Author |
Takahiro Horimatsu |
Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East |
| Author |
Atsushi Katagiri |
Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East |
| Author |
Kuang-I Fu |
Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East |
| Author |
Manabu Muto |
Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East |
| Author |
Yutaka Saito |
Division of Endoscopy, National Cancer Center Hospital |
| Author |
Takahisa Matsuda |
Division of Endoscopy, National Cancer Center Hospital |
| Author |
Shigeaki Yoshida |
Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East |
| [ Summary ] |
We reviewed magnified observation of the microvascular architecture of colorectal lesions and examined the utility of detailed observation of the microvascular architecture for differential diagnosis during narrow band imaging (NBI) colonoscopy. Angiogenesis is critical to the transition of premalignant lesions in a hyperproliferative state to the malignant phenotype. Therefore, diagnosis based on angiogenic or vascular morphologic changes may be ideal for early detection or diagnosis of neoplasms. In this review, we propose the term “meshed capillary” for the distinction between nonneoplastic and neoplastic lesions and the capillary classification “capillary pattern” for the differential diagnosis of colorectal lesions. We believe that the combined use of NBI optical chromoendoscopy and real chromoendoscopy decreases the time and cost of screening colonoscopy. To assess the feasibibty and efficacy of using the NBI system, further studies are required of colorectal and other lesions of the gastrointestinal tract. |