| Theme | Obesity and Digestive Organ | |
|---|---|---|
| Title | Diet Therapy and Exercise Therapy for Obesity‒related Diseases | |
| Publish Date | 2019/04 | |
| Author | Satoru Yamazaki | Second Department of Internal Medicine, Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology, Graduate School of Medicine, University of the Ryukyus / Department of Diabetes, Endocrinology and Metabolism, School of Medicine, Fukushima Medical |
| Author | Emi Ogata | Second Department of Internal Medicine, Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology, Graduate School of Medicine, University of the Ryukyus / Department of Diabetes, Endocrinology and Metabolism, School of Medicine, Fukushima Medical |
| Author | Hiroaki Masuzaki | Department of Diabetes, Endocrinology and Metabolism, School of Medicine, Fukushima Medical University |
| [ Summary ] | Diet therapy and exercise therapy are the basis of obesity treatment. Both therapies are effective for reducing body weight, and metabolism is improved depending on the amount of weight lost. In diet therapy, the goal for reducing weight is 3 % from the present body weight for obesity and 5-10 % for morbid obesity. In addition to the content of the meal, animal fat addiction has been reported; therefore, revealing the mechanism between the control of dietary behavior and the Brain‒Reward‒System could be a breakthrough in future diet therapy. Exercise therapy is effective for reducing weight and has the possibility to improve the quality of life of obese patients. Because skeletal muscle decreases with aging and leads to an increase in mortality rate, developing a strategy to prevent sarcopenia is important. Interestingly, the endocrine action of skeletal muscle has been elucidated in recent studies. That is, the skeletal muscle could be the largest endocrine organ. Furthermore, the mechanism of how exercise acts on the brain has been elucidated, and exercise therapy is greatly anticipated for its positive effect on the brain. |
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